A whole chromosome abnormality means an entire chromosome is missing (monosomy) or duplicated (trisomy). It can affect every cell in the embryo (whole chromosome aneuploid) or only some cells (whole chromosome mosaic). Whole chromosome aneuploids have a very low chance of resulting in a live birth, while whole chromosome mosaics have intermediate success rates.
Synonyms:
whole chromosome, whole chromosomes, whole chromosomal