Pre-implantation genetic testing (PGT) is a common add-on for patients undergoing IVF, which involves testing some of the cells of an embryo for chromosomal abnormalities.
There are several forms of PGT:
- PGT-A = PGT for aneuploidy (to select for euploids with the correct number/structure of chromosomes; also called PGS testing, or comprehensive chromosomal screening/CCS).
- PGT-M = PGT for monogenic/single gene defects (like cystic fibrosis; also called PGD)
- PGT-SR = PGT for structural rearrangements (like for translocations)
PGT-M and PGT-SR are more personalized treatments that involve examining the genetics of the parents, to provide more sensitive PGT results compared to PGT-A.
You can read more about PGT in my Complete guide to PGT-A.
Synonyms:
PGS, CCS, PGT, PGT-M, PGT-SR, PGT-A