UWOF #19: Live birth from day 3 fragmented embryos

With most embryos arresting and one cycle already failed, a patient transferred three fragmented day 3 embryosโ€”and welcomed a healthy baby girl.

๐Ÿ’ฌ These stories are part of the Uterine Wall of Fame โ€” a growing collection of real IVF success stories submitted by patients who faced challenging scenarios like poor-quality embryos or low AMH. The UWOF is a project by Remembryo / Embryoman, a site that highlights new IVF research. All UWOF posts are free to access (no subscription required).

โš ๏ธ These stories are personal experiences, not medical advice or scientific evidence. Success stories are more likely to be shared than unsuccessful ones, so they should not be interpreted as proof that a treatment works. Always discuss treatment decisions with your doctor.

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๐Ÿ“Š Story Snapshot ๐Ÿ‘ฉ Age: Not stated
๐Ÿ“† Years trying: Not stated
๐Ÿงฌ Embryo: 3 day 3 embryos, poor quality
๐Ÿงช Retrievals: 2
๐Ÿฃ Transfers: 1
๐Ÿ’Š Diagnosis: Male factor infertility
๐Ÿ“ˆ Outcome: Live birth

We did a second round of IVF after a completely failed first round with no frozen embryos out of 8 fertilized. We have male factor infertility and it was the worst sample my husband ever gave, and that is saying something.

6 of our 9 fertilized embryos arrested even before this day 3 transfer, and the 3 remaining embryos underwent direct cleavage (cell division one to two cells then very quickly jumping to 5 cells, as seen on an embryo scope) and were very poor quality (5 cells on day 3 and highly fragmented). I cried as they brought me a picture of the 2 embryos they wanted to transfer: I asked if we could cancel the transfer and get our money back.ย 

Seeing me upset they asked if we wanted to do a hail Mary and throw in all 3 because thatโ€™s all we had. They brought a picture of all 3 left, and the new embryo in the picture that they almost left to inevitably die in the lab had much more symmetric cells and even โ€œprettierโ€ fragmentation than the two they originally wanted to transfer.

I knew it wouldnโ€™t work, so I didnโ€™t even test beforehand: I had zero hope. Well, I was SHOCKED when I got the call that my pregnancy test was positive, and I almost thought they had mixed up my lab results with someone elseโ€™s. And now one of those embryos is my 28 month old daughter, perfectly healthy!!!ย ย 

In all the studies I read, direct cleavage alone is a death sentence for an embryo and 1 to 5 cell cleavage is pretty much unheard of (1 to 3 or even 4 being more common), all the more so direct cleavage resulting in a slow-growing, highly fragmented embryo.ย  Iโ€™m convinced my daughter is the embryo we almost left behind in the lab, and I donโ€™t think she would have survived there since all 16 of our others died before they could be frozen: itโ€™s as if my tears saved her life! I still canโ€™t believe her story to this day even though we lived it!


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You can explore similar IVF success stories by clicking the IVF Success tags below, browse the full archive here, or visit the Uterine Wall of Fame homepage.

Want to learn more about poor quality embryos? Check out my guide on poor quality embryo success rates.

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