After 8 IVF cycles, multiple miscarriages, and Hashimoto’s disease, this parent achieved a successful pregnancy at age 42 using untested embryos and aggressive immune treatment — including IVIG, neupogen, steroids and hydroxychloroquine.
⚠️ These stories are personal experiences, not medical advice or scientific evidence. Success stories are more likely to be shared than unsuccessful ones, so they should not be interpreted as proof that a treatment works. Always discuss treatment decisions with your doctor.
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📊 Story Snapshot
👩 Age: 41📆 Years trying: 5
🧬 Embryo: 2x Day 2 + 1x Day 5 (untested)
🧪 Retrievals: 8
🐣 Transfers: Not stated
💊 Diagnosis: Immune-related issues, Recurrent pregnancy loss, Thyroid or autoimmune condition
📈 Outcome: Live birth (now 3.5 years old)
We started trying to conceive when I was 36 and my husband was 43. We did 4 rounds of IUI and had a chemical pregnancy during the last round. We then did 8 rounds of IVF before we had success. We had to fight autoimmune hashimotos, extremely high DNA fragmentation, high NK cells and high cytokines, implantation failure despite numerous euploids, recurrent miscarriages of euploid and untested embryos and consultants who did not believe in immune treatment.
We went abroad, we tried different clinics & finally we found a clinic which closely monitored, did IVIG, neupogen washes, steroids, hydroxychloroquine, viagra to improve lining, high dose progesterone etc etc. We threw the kitchen sink at our successful cycle and did a split transfer of 2x fresh day 2 embryos plus a frozen day 5 embryo — all untested and we got success! I was 42 at the time and used my own eggs.
During pregnancy I was high risk of 2nd trimester loss and needed very high dose progesterone & an emergency cervical suture and bed rest!
Our child is truly a miracle from God and a miracle of science…
What would you say to someone who’s going through what you went through?
“IVF is tough – whether it is one cycle or 10.
Keep fighting your corner. Keep reading the latest research and keep up to date. Challenge when you need to. Take a step back and grieve when you need to.
Be kind to yourself and your partner
I learnt something new about my body and my journey with each failed cycle which eventually helped us have success.
Good luck”
Looking for more stories like this one?
You can explore similar IVF success stories by clicking the IVF Success tags below, browse the full archive here, or visit the Uterine Wall of Fame homepage.
Want to learn more about how the immune system impacts fertility? Check out my guide on the role of the immune system in infertility and IVF.
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