A 2026 study of over 227,000 IVF couples found that chromosomal abnormalities were uncommon but more frequent than in the general population, and were most strongly linked to recurrent miscarriage, poor sperm quality, and younger age.
Male factor infertility
A 2025 review found that men with infertility are more likely to have certain health conditions, but the reasons aren’t clear and the overall risks are still low, suggesting that fertility testing can be a good chance to check on general health.
A 2025 randomized trial found that men who took the combined antioxidant supplement Impryl for six months had no improvement in semen quality or pregnancy rates, and in some cases slightly worse outcomes, suggesting that routine antioxidant use may do more harm than good for some male infertility patients.
A large 2025 study of donor egg cycles found that poor fertilization in IVF is uncommon, but when it does occur it’s usually caused by sperm rather than the egg. Most cases of low fertilization were sperm-related, while only a minority were linked to eggs or other factors.
Researchers in a 2023 study compared PGT-A outcomes for patients with different diagnoses, including advanced maternal age (AMA), recurrent implantation failure (RIF), recurrent pregnancy loss (RPL) and severe male factor (SMF).
Researchers in a 2023 study found that increasing female BMI resulted in decreased pregnancy and live birth rates after a single euploid transfer, while pregnancy loss rates increased. This effect was reduced in cases of male factor infertility only, suggesting that weight itself may not be responsible.