Researchers in a 2026 study found that natural FETs using donor eggs were linked to higher live birth rates, lower miscarriage rates, and lower rates of some pregnancy complications compared to medicated FETs.
Perinatal and obstetric outcomes
A 2025 study of single-blastocyst transfers found no increase in birth defects or adverse pregnancy outcomes when transferring poor quality embryos compared to good quality ones.
The ASRM has released their 2024 committee opinion on the use of PGT-A, covering the use of PGT-A for patients with a good prognosis, advanced age, donor eggs, recurrent pregnancy loss and more.
Researchers in a 2024 study found no health problems in children born from mosaic embryo transfers, with an average age of 3 years. They also found no differences in obstetric outcomes between mosaic and euploid transfers.
This post reviews what research currently shows about the vaginal and endometrial microbiome and how it may relate to fertility and IVF outcomes. While Lactobacillus species are often considered beneficial and are commonly found in the reproductive tract, studies examining whether microbiome differences actually affect IVF success have produced mixed results.
Researchers in a 2023 study found decreased adverse pregnancy and neonatal outcomes in those who performed a natural vs medicated FET, including abnormal birth weights, preeclampsia, preterm births, and more.
Researchers in a 2022 study compared perinatal outcomes after IVF using donor sperm and found a reduction in preterm births, low birth weights and congenital anomalies compared to babies conceived using partner sperm.
Researchers in a 2022 study found that women with low β-hCG (<149 mUI/ml) are more likely to have a preterm delivery and abnormal placental pathologies compared to women with higher β-hCG.
Researchers in a 2022 study performed a systematic review and meta-analysis on women with endometriosis undergoing IVF and found no change in live birth rates, but an increased risk of obstetric and perinatal outcomes, however patients were diagnosed without laparoscopy and didn’t account for treated patients.