Researchers in a 2023 study compared PGT-A outcomes for patients with different diagnoses, including advanced maternal age (AMA), recurrent implantation failure (RIF), recurrent pregnancy loss (RPL) and severe male factor (SMF).
Implantation failure
Researchers in a 2023 study developed a model to predict the chance of live birth after a positive β-hCG (beta-hCG), using the first measurement and a second one taken 48 hours later.
Researchers in a 2023 study found that probiotic supplementation had no impact on positive hCG pregnancy rates, but may improve miscarriage rates.
This post reviews what research currently shows about the vaginal and endometrial microbiome and how it may relate to fertility and IVF outcomes. While Lactobacillus species are often considered beneficial and are commonly found in the reproductive tract, studies examining whether microbiome differences actually affect IVF success have produced mixed results.
Researchers in a 2023 study combined the results of 74 studies to investigate what factors contribute to euploid live birth and miscarriage rates, identifying embryo quality, maternal age, specific diagnoses, repeat freeze/thaw, and other factors.
Researchers in a 2023 study discovered 6 genes associated with recurrent miscarriage of euploid embryos, which were found to impair reproductive ability in mouse models.
Researchers in a 2022 study found no difference in live birth rates in those that transferred embryos by standard timing or timing established by the ERA.
Researchers in a 2022 study performed a meta-analysis to combine the results of 8 ERA studies and found no differences in live birth, pregnancy and miscarriage rates among women who performed the ERA or didn’t.
Researchers in a 2022 study found no benefit in patients who used the ERA after transferring a single euploid, even when accounting for a history of failed transfers.
Researchers in a 2022 study compared the impact of endometrial thickness on pregnancy outcomes in fresh and frozen embryo transfer cycles.
Researchers in a 2019 study compared pregnancy outcomes with different serum β-hCG levels that were measured on day 16 of the embryo’s age (13dp3dt/11dp5dt).
This post covers the variety of reasons embryos can fail to implant or miscarry, including as a result of advanced maternal age, chromosomal translocations, lifestyle, endometritis, the microbiota, immunological issues, endometrial receptivity, the clinic, and more. Note that this is not a complete list, and will be updated periodically.
Researchers in a 2020 study found that sperm from males in couples with recurrent pregnancy loss were more likely to be aneuploid, potentially leading to the diagnosis.
Not sure what your embryo grade means—or if it affects your chances of success? This guide walks you through everything from day 3 and day 5 grading systems to what each number and letter combo (like 3BB or 5AA) actually means. You’ll also find success rate research, embryo photos, and insights from a former embryologist to help make sense of your report.