Researchers in 2024 report on live births after segmental aneuploid transfers, finding that they have similar rates as high level mosaic segmental aneuploids.
A 2024 case report details a patient who had success transferring a 4 cell embryo on day 4 — an embryo that some clinics wouldn’t have considered for transfer.
A 2024 meta-analysis combined the results of 38 studies investigating treatments for diminished ovarian reserve patients. DHEA, testosterone, high-dose gonadotropins and delayed start protocols all improved the number of eggs retrieved.
A 2024 randomized controlled trial (RCT) found that Zymot-selected sperm didn’t improve embryo euploidy rates, but increased fertilization rates. An important limitation of this study is that it was done in the general IVF population and not in individuals with high sperm DNA fragmentation.
A 2024 study performed a more sensitive type of PGT-A by analyzing single cells, finding that nearly all blastocysts and fetal tissue contain some level of mosaicism.
A 2024 study found that beta-hCG levels were related to day 3 and day 5 embryo quality and development, with blastocyst expansion having the strongest impact on both initial beta values and their doubling.
A 2024 study compared IVF outcomes and pregnancy rates for patients of different ages (<32 to >40) who had their first single embryo transfer.
Aneuploid embryos, with an abnormal number of chromosomes, are a major cause of miscarriages, often linked to maternal age and errors in meiosis. In this post, we’ll explore what chromosomes and aneuploidy are, how meiosis errors cause aneuploidy, and the factors contributing to these errors, including age, genetics and mitochondrial dysfunction.
A 2024 meta-analysis combined the results of 20 studies, showing that supplements improved IVF outcomes in women with ovarian aging, especially CoQ10.
A 2024 study found that patients with recurrent pregnancy loss have congenital uterine anomalies at a rate of 8-19%, with 23% having adenomyosis.
A 2024 study combined studies involving unexplained infertility patients and endometriosis, finding that nearly half of them have the condition.
A 2024 study compared successful and unsuccessful euploid transfers, finding that female age had no impact, while BMI, embryo quality and the type of FET used did.
In a 2024 study, researchers developed a model to help predict the number of mature eggs needed to obtain at least one euploid, based on age.
Successful embryo implantation and pregnancy depends on careful control of the immune system. In this post, we’ll explore the general workings of the immune system and its role in pregnancy, examining how dysregulation of immune cells like natural killer (NK) cells and macrophages can impact fertility. Additionally, we’ll look into autoimmunity and discuss how immunotherapies may be used to improve IVF outcomes.
The ASRM has released their 2024 committee opinion on the use of PGT-A, covering the use of PGT-A for patients with a good prognosis, advanced age, donor eggs, recurrent pregnancy loss and more.