“True” recurrent implantation failure is rare after five consecutive euploid embryo transfers

Researchers in a 2024 study found that patients that have 5 consecutive euploid transfers had a cumulative live birth rate of 98.1%, suggesting that most cases of implantation failure are due to the embryo, and that true unexplained RIF occurs in less than 2% of patients.

Researchers develop tool to help predict fertilization failure

Researchers in a 2024 study identified what factors were involved in fertilization failure and built a nomogram (calculator) to help predict when this happens, with moderate predictive ability.

Lower cumulative live birth rates with certain forms of endometriosis

Researchers in a 2024 study found lower cumulative live birth rates in patients with a particular type of endometriosis (DIE and/or ovarian endometrioma) that was diagnosed using transvaginal ultrasound.

PGT-A cost analysis for first-cycle transfers across age groups

Researchers in a 2024 study compared the costs of patients with or without PGT-A, finding that patients younger than 35 may not benefit because of the higher chance of top-graded embryos being euploid anyway.

Patients with or without endometriosis have similar live birth rates after PGT-A

Researchers in a 2023 study found that patients with or without endometriosis have comparable live birth rates after transferring a euploid embryo, although patients may have been surgically treated (a limitation). Endometriosis patients are more likely to produce aneuploid embryos.