Researchers develop tool to help predict fertilization failure

Researchers in a 2024 study identified what factors were involved in fertilization failure and built a nomogram (calculator) to help predict when this happens, with moderate predictive ability.

Lower cumulative live birth rates with certain forms of endometriosis

Researchers in a 2024 study found lower cumulative live birth rates in patients with a particular type of endometriosis (DIE and/or ovarian endometrioma) that was diagnosed using transvaginal ultrasound.

PGT-A cost analysis for first-cycle transfers across age groups

Researchers in a 2024 study compared the costs of patients with or without PGT-A, finding that patients younger than 35 may not benefit because of the higher chance of top-graded embryos being euploid anyway.

Patients with or without endometriosis have similar live birth rates after PGT-A

Researchers in a 2023 study found that patients with or without endometriosis have comparable live birth rates after transferring a euploid embryo, although patients may have been surgically treated (a limitation). Endometriosis patients are more likely to produce aneuploid embryos.

POPI-Plus calculator predicts chance of live birth after positive beta-hCG

Researchers in a 2023 study developed a model to predict the chance of live birth after a positive β-hCG (beta-hCG), using the first measurement and a second one taken 48 hours later.

Explaining Unexplained Infertility through Non-Surgical Endometriosis Diagnosis

Laparoscopy is the gold standard for diagnosing endometriosis, but other non-surgical tests are showing potential. Here we’ll take a brief look at ReciptivaDx based on the BCL6 protein, the Endotest and DotEndo test based on a miRNA signature, the EMScore which is based on a gene expression signature, and imaging tests like ultrasound and MRI.

ESHRE 2023 guidelines on managing unexplained infertility

Researchers in 2023 provide evidence-based guidelines for managing patients with unexplained infertility, as prepared by ESHRE.