A day 6 mosaic embryo led to pregnancy at 41 for a patient who had undergone trachelectomy, faced cancer, and endured 13 IUIs and multiple losses.
Embryoman
After eight years of unexplained infertility and two embryo transfers, this patient became pregnant with twins from mosaic embryos carrying a rare inherited genetic variant.
After three retrievals and repeated embryo fragmentation by Day 2, a single poor quality blastocyst developed and led to the birth of a healthy baby boy.
A downgraded 4BC embryo led to pregnancy for a 37-year-old patient, after two failed FETs with higher-graded euploid embryos and a shift in protocol.
After four retrievals and several failed transfers, a frozen 4BC embryo that didn’t fully re-expand after thawing led to a healthy 21-week pregnancy and normal NIPT and anatomy scan results.
A new study showed that day 7 embryos may develop more slowly because of stress and disrupted signaling in the inner cell mass, which might help explain their lower success rates.
A 2025 meta-analysis found that while 1PN zygotes don’t convert to blastocyst as well and have lower success rates when untested, those confirmed as euploid can lead to healthy births, but extra care is needed to confirm they are truly normal.
A 2025 study found that nearly one in three IVF patients without PCOS or diabetes had insulin resistance, which was linked to lower success rates, but taking metformin before embryo transfer seemed to help.
A pilot study in 2025 explored whether mitochondrial DNA mutations in follicular fluid could reflect egg quality, finding some early signs of a possible link, but there were some significant limitations.
A 2025 study found that PCX, a surface molecule on endometrial cells, may lead to a shorter implantation window in women with endometriosis and might explain the stickiness of lesions outside the uterus.
A new study found that selecting FSH type based on a woman’s FSH receptor (FSHR) genotype may improve IVF pregnancy and live birth rates, particularly when using rFSH for NN genotypes and uFSH for NS or SS genotypes.
This post summarizes the 2025 ESHRE/ALPHA Istanbul consensus on egg and embryo assessment, offering patients a clear overview of how embryologists evaluate and rank eggs, zygotes, and embryos based on updated international guidelines.
In a 2025 study, researchers estimated how many frozen eggs are needed, by age, to reliably yield three euploid blastocysts or achieve one, two or three live births, offering practical guidance for egg freezing patients.
Researchers in a 2025 study found that women with RPL show distinct immune-related gene activity in their endometrium, identifying a possible molecular signature that could help diagnose or personalize treatment for RPL in the future.
Researchers performed rescue IVM on immature eggs collected from poor prognosis patients, and found that a large number became mature and fertilized, allowing about 1 in 12 patients to have a live birth that they wouldn’t have had otherwise.
